citrulline

noun

cit·​rul·​line ˈsi-trə-ˌlēn 

: a crystalline amino acid C₆H₁₃N₃O₃ formed especially as an intermediate in the conversion of ornithine to arginine

Examples of citrulline in a Sentence

Recent Examples on the Web

Studies have not determined if one type of citrulline is better.2 When buying a supplement, make sure the product is independently tested. —Kirstyn Hill, Pharmd, Mph, Health, 19 Mar. 2025

Relieves Sore Muscles from Exercise Watermelon contains an amino acid called citrulline, which increases blood concentrations of L-arginine (an amino acid that helps the body build protein). —Lindsey Desoto, Rd, Ld, Verywell Health, 29 Jan. 2025

Watermelon: Watermelon has high concentrations of citrulline, an amino acid that may enhance blood flow and lessen the risk of ED. —Amber Smith, Discover Magazine, 15 Jan. 2023

This supplement is made with a unique 2-in-1 formula that includes L-citrulline and longjack 100 to boost testosterone production while supporting balanced levels. —The Salt Lake Tribune, 8 Nov. 2022

Word History

Etymology

International Scientific Vocabulary, from New Latin Citrullus, genus name of the watermelon

First Known Use

1930, in the meaning defined above

Rhymes for citrulline

• acridine
• alkaline
• andesine
• anodyne
• anticline
• arginine
• asinine
• atropine
• benzidine
• borderline
• byzantine
• calamine

Medical Definition

citrulline

noun

cit·​rul·​line ˈsi-trə-ˌlēn; si-ˈtrəl-ˌēn, -ən 

: a crystalline amino acid C₆H₁₃N₃O₃ formed especially as an intermediate in the conversion of ornithine to arginine in the living system