Medical Dictionary

brain-derived neurotrophic factor

noun

medical Definition of brain-derived neurotrophic factor

: a neuropeptide that regulates the growth, survival, and differentiation of neurons and that affects synaptic plasticity especially by mediating long-term potentiation
  • Brain-derived neurotrophic factor … is critical for axonal growth, neuronal survival, and synaptic plasticity, and its levels are affected by stress and cortisol.
  • —R. H. Belmaker and Galila AgamThe New England Journal of Medicine3 Jan. 2008
  • Out of the variety of neurotrophic factors released during exercise, however, scientists found that one in particular stood out: brain-derived neurotrophic factor
  • —Christen BrownleeScience News25 Feb. 2006
abbreviation BDNF

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