au·to·phos·phor·y·la·tion
| \ ˌȯ-tō-ˌfäs-ˌfȯr-ə-ˈlā-shən
\
\
Medical Definition of autophosphorylation
: phosphorylation of an organic compound (such as an enzyme) by its own residues
Accordingly, if the autophosphorylation of receptor tyrosine kinases is suppressed pharmacologically, the assembly of the downstream signaling complexes may be halted, providing a chance to slow the progression of certain cancers.— John D. Scott and Tony Pawson, Science, 27 Nov. 2009
Other Words from autophosphorylation
autophosphorylate
\
ˌȯ-tō-ˌfäs-ˈfȯr-ə-ˌlāt
\
transitive verb
autophosphorylated; autophosphorylating
\
transitive verb
autophosphorylated; autophosphorylating
The intracellular β-subunit regions, like that of the EGF [epidermal growth factor] receptor, possess tyrosine kinase activity and a tyrosine residue that is autophosphorylated in response to insulin binding.
— Keith Wilson, in Principles and Techniques of Practical Biochemistry, 5th edition, 2000
Learn More about autophosphorylation
Dictionary Entries near autophosphorylation
See More Nearby EntriesCite this Entry
“Autophosphorylation.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/autophosphorylation. Accessed 11 Apr. 2021.
Style: MLA
MLA
Chicago
APA
Merriam-Webster
Chicago
APA
Merriam-Webster
Comments on autophosphorylation
What made you want to look up autophosphorylation? Please tell us where you read or heard it (including the quote, if possible).
Test Your Vocabulary
The Exceptions Quiz III
-
- Which of these words does not mean "nonsense"?
Test your knowledge - and maybe learn something along the way.
TAKE THE QUIZ
Spell words. Make bears.
TAKE THE QUIZLove words? Need even more definitions?
Merriam-Webster unabridged
Words at Play
Ask the Editors
Share autophosphorylation