autophosphorylation
noun
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Medical Definition of autophosphorylation
: phosphorylation of an organic compound (such as an enzyme) by its own residues Accordingly, if the autophosphorylation of receptor tyrosine kinases is suppressed pharmacologically, the assembly of the downstream signaling complexes may be halted, providing a chance to slow the progression of certain cancers. —John D. Scott and Tony Pawson, Science, 27 Nov. 2009
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