Medical Dictionary

assisted hatching

noun as·sist·ed hatching \ ə-ˌsis-təd- \

medical Definition of assisted hatching

: a technique for assisting reproduction in cases of infertility that involves manipulating (as by creating a small opening in) the zona pellucida of a fertilized egg usually a few days after in vitro fertilization to facilitate its implantation in the uterine endometrium
  • Assisted hatching involves the disruption of the zona pellucida before the embryo transfer to potentially enhance implantation.
  • —Beth A. Malizia et al.The New England Journal of Medicine15 Jan. 2009

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