Medical Definition of aptamer
: a short segment of DNA, RNA, or peptide that binds to a specific molecular target (such as a protein) This aptamer works by binding and blocking a major molecule involved in the body's blood-clotting reaction, called thrombin.— Debora MacKenzie, New Scientist, 6 Oct. 2006 Aptamers … are isolated by … the repetitive screening of large pools of randomized molecules for those that bind best to a target. — Chemical & Engineering News, 15 Mar. 1993
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