Medical Dictionary

aprotinin

noun apro·ti·nin \ ā-ˈprōt-ə-nin \

medical Definition of aprotinin

:a polypeptide with protease-inhibiting properties formerly used to reduce blood loss and preserve platelet function during heart surgery but now withdrawn from use due to safety concerns
  • Based on our data, we therefore believe that additional concern is now warranted regarding the long-term safety of aprotinin among patients undergoing coronary artery bypass surgery.
  • —Dennis T. Mangano et al.The Journal of the American Medical Association7 Feb. 2007

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