medical Definition of aprotinin
: a polypeptide with protease-inhibiting properties formerly used to reduce blood loss and preserve platelet function during heart surgery but now withdrawn from use due to safety concerns
- Based on our data, we therefore believe that additional concern is now warranted regarding the long-term safety of aprotinin among patients undergoing coronary artery bypass surgery.
- —Dennis T. Mangano et al., The Journal of the American Medical Association, 7 Feb. 2007
