Medical Dictionary

angiostatin

noun an·gio·stat·in \ ˈan-jē-ə-ˌsta-tᵊn \

medical Definition of angiostatin

: a naturally-occuring protein that is derived from the cleavage of plasminogen and that inhibits the formation and growth of blood vessels
  • angiostatin shrinks blood vessel growth by binding to and shutting down ATP synthase, an enzyme on an endothelial cell's surface. It thereby cuts off the energy required for blood vessel growth.
  • —Gary StixScientific AmericanJune 1999

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