Medical Dictionary


noun am·y·lin \ˈa-mə-lən\

Medical Definition of amylin

  1. :  a pancreatic polypeptide hormone that is secreted with insulin by the beta cells of the islets of Langerhans, that is a major component of the amyloid deposits found outside beta cells in those affected with type 2 diabetes, and that inhibits the glucose synthesis stimulated by insulin in skeletal muscles <Released by the same pancreatic cells that secrete insulin, amylin modulates the effects of insulin on other cells, but efforts to identify a single protein that serves as its receptor have failed.—Terry Kenakin, Scientific American, October 2005> <Pramlintide is an analogue of the islet cell-secreted hormone amylin that acts through the brainstem to reduce food intake and cause weight loss.—Jonathan Q. Purnell, ACP Medicine, October 2008>—called also islet amyloid polypeptide

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