Medical Dictionary

amylin

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noun am·y·lin \ˈa-mə-lən\

Medical Definition of amylin

  1. :  a pancreatic polypeptide hormone that is secreted with insulin by the beta cells of the islets of Langerhans, that is a major component of the amyloid deposits found outside beta cells in those affected with type 2 diabetes, and that inhibits the glucose synthesis stimulated by insulin in skeletal muscles Released by the same pancreatic cells that secrete insulin, amylin modulates the effects of insulin on other cells, but efforts to identify a single protein that serves as its receptor have failed.—Terry Kenakin, Scientific American, October 2005 Pramlintide is an analogue of the islet cell-secreted hormone amylin that acts through the brainstem to reduce food intake and cause weight loss.—Jonathan Q. Purnell, ACP Medicine, October 2008—called also islet amyloid polypeptide


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