medical Definition of amastigote
- For all species of Leishmania, the portion of the life cycle spent in mammalian hosts is paradoxical in that the amastigote infects macrophages, the very cells of the mammalian host that constitute its primary defense against invasion by foreign organisms.
- —Burton J. Bogitsh et al., Human Parasitology, 2005
- In the sandfly gut the amastigotes leave the host cell, transform into promastigotes, and replicate extracellularly.
- —David J. Wyler and Anthony R. Mattia, The New England Journal of Medicine, 17 Mar. 1994