amastigote

noun

amas·​ti·​gote (ˈ)ā-ˈma-stə-ˌgōt How to pronounce amastigote (audio)
: the nonmotile, parasitic form in the life cycle of some protozoans (family Trypanosomatidae, and especially genus Leishmania) that usually develops in the cells of vertebrate hosts and occurs as a minute, ovoid or spherical body with a prominent, rod-shaped kinetoplast and a rudimentary, internal flagellum arising from a basal body
For all species of Leishmania, the portion of the life cycle spent in mammalian hosts is paradoxical in that the amastigote infects macrophages, the very cells of the mammalian host that constitute its primary defense against invasion by foreign organisms.Burton J. Bogitsh et al., Human Parasitology
In the sandfly gut the amastigotes leave the host cell, transform into promastigotes, and replicate extracellularly.David J. Wyler and Anthony R. Mattia, The New England Journal of Medicine

Dictionary Entries Near amastigote

Cite this Entry

“Amastigote.” Merriam-Webster.com Medical Dictionary, Merriam-Webster, https://www.merriam-webster.com/medical/amastigote. Accessed 25 Jul. 2024.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!