Medical Dictionary

alteplase

noun al·te·plase \ ˈal-tə-ˌplās \

medical Definition of alteplase

: a recombinant form of tissue plasminogen activator that is used to prevent damage to heart muscle following a heart attack and to reduce neurological damage following ischemic stroke
  • Intravenous thrombolytic treatment with alteplase, initiated within 3 hours after the onset of symptoms, is the only medical therapy currently available for acute ischemic stroke.
  • —Werner Hacket et al.The New England Journal of Medicine25 Sept. 2008
Note: Alteplase is marketed under the trademark Activase.

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