Medical Definition of alteplase
: a recombinant form of tissue plasminogen activator that is used to prevent damage to heart muscle following a heart attack and to reduce neurological damage following ischemic stroke Intravenous thrombolytic treatment with alteplase, initiated within 3 hours after the onset of symptoms, is the only medical therapy currently available for acute ischemic stroke.— Werner Hacket et al., The New England Journal of Medicine, 25 Sept. 2008
Note: Alteplase is marketed under the trademark Activase.
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