al·pha-block·er | \ -ˌbläk-ər 
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\Medical Definition of alpha-blocker
: any of a group of drugs (as doxazosin and terazosin) that combine with and block the activity of an alpha-receptor to relax smooth muscle (as of blood vessels) and are used especially to treat hypertension and benign prostatic hyperplasia — compare beta-blocker
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