Medical Dictionary

adeno-associated virus

noun ad·e·no-as·so·ci·at·ed virus \ ˌa-də-ˌnō-ə-ˌsō-shē-ˌā-təd-, -sē- \

medical Definition of adeno-associated virus

:any of several single-stranded DNA viruses (genus Dependovirus of the family Parvoviridae) that enter the nucleus of a host cell but are dependent on coinfection with an adenovirus or herpesvirus for their replication, that infect a wide range of hosts but do not appear to cause disease, and that are used in gene therapy as vectors to introduce genes into cells
  • Both groups also used as a vector a small adeno-associated virus that infects humans and other primates but is not known to cause disease. Its safety has been shown in various gene therapy experiments.
  • —Thomas H. Maugh IIThe Los Angeles Times28 Apr. 2008
abbreviation AAV

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