acantholysis

noun
ac·an·thol·y·sis | \ ˌak-ˌan-ˈthäl-ə-səs , ˌā-ˌkan- , ˌak-ən- \
plural acantholyses\-ə-ˌsēz \

Medical Definition of acantholysis 

: loss of coherence between keratinocytes of the epidermis that is due to breakdown of desmosomal intercellular attachments and is characteristic of various conditions (as pemphigus and herpesvirus infection) marked by vesicular eruption

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