, William (1804–1878)
British physician. Stokes produced more than 140 books and articles, covering such medical topics as intestinal disorders, mediastinal tumors, hydrocephalus, cerebrospinal meningitis, cancer of the mouth, and sarcoma of the scrotum. His most important works were concerned with diseases of the chest, heart, and aorta. His book Diseases of the Chest (1837) was the first treatise on the subject in modern medicine. His 1846 description of heart block, described previously by Giovanni Morgagni and later by Robert Adams, was a classic, detailed description that was based on case histories from several sources. In 1854 Stokes used John Cheyne's observations on respiration as a point of departure and wrote an extended description of the condition now known as Cheyne-Stokes respiration.
Adams, Robert (1791–1875),
British physician. Adams enjoyed a high reputation as a surgeon and specialist in pathological anatomy. He practiced medicine at several Dublin hospitals. His most important scientific contributions were made in cardiology and the autopsies of patients suffering from various cardiac disorders. He associated cerebral symptoms and slowing of the pulse with cardiac disease. This phenomenon had been noted earlier by Morgagni and would be confirmed later by William Stokes. Adams published his monograph on diseases of the heart in 1827.