Medical Dictionary

Schultz-Dale reaction

noun \ ˈshu̇ltz-ˈdāl- \

medical Definition of Schultz-Dale reaction

: a reaction of anaphylaxis carried out in vitro with isolated tissues

Biographical Note for schultz-dale reaction

  • Dale, Sir Henry Hallet (1875–1968), British physiologist and pharmacologist. Dale was one of the outstanding physiologists and pharmacologists of the first half of the 20th century. His early research work centered on the physiological actions of ergot. His work with isolated guinea pig uteri established that the anaphylactic antibodies are attached to cells. He reported on the results of his research on anaphylaxis in 1919. For their discoveries in the chemical transmission of nerve impulses, he and the German pharmacologist Otto Loewi were awarded the Nobel Prize for Physiology or Medicine in 1936.

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