Medical Definition of Sandhoff's disease
: a hereditary disorder of lipid metabolism that is closely related to or a variant of Tay-Sachs disease, typically affects individuals of non-Jewish ancestry, and is characterized by great reduction in or absence of both hexosaminidase A and hexosaminidase B
Biographical Note for sandhoff's disease
Andreae \än-ˈdrā-e\play ,
H., German medical scientists. Sandhoff, Andreae, and Jatzkewitz jointly published a description of a variant form of Tay-Sachs disease in 1968. They based their report on three typical cases of Tay-Sachs, one exceptional case, and seven controls.
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