Sand·hoff's disease | \ ˈsand-ˌhȯfs- 
\
\variants:
or Sandhoff disease \ -ˌhȯf- \
\Medical Definition of Sandhoff's disease
: a hereditary disorder of lipid metabolism that is closely related to or a variant of Tay-Sachs disease, typically affects individuals of non-Jewish ancestry, and is characterized by great reduction in or absence of both hexosaminidase A and hexosaminidase B
Comments on Sandhoff's disease
What made you want to look up Sandhoff's disease? Please tell us where you read or heard it (including the quote, if possible).
Test Your Vocabulary
Words of Snow and Ice Quiz
- Which of the following refers to thin, bending ice, or to the act of running over such ice?
Test your knowledge - and maybe learn something along the way.
TAKE THE QUIZ
Anagram puzzles meet word search.
TAKE THE QUIZLove words? Need even more definitions?
Merriam-Webster unabridgedWords at Play
Ask the Editors
Word Games
- Words of Snow and Ice Quiz
A selection of words from the chillier parts of t...
Take the quiz - Name that Thing: Toys and Games Edition
It's all fun and games until someone beats your h...
Take the quiz - True or False?
Test your knowledge - and maybe learn something a...
Take the quiz - SCRABBLE® Sprint
SCRABBLE® fans, sharpen your skills!
Play the game
Share Sandhoff's disease