medical Definition of Philadelphia chromosome
- A bone marrow test the next day revealed a genetic abnormality called the Philadelphia chromosome that is the signature of chronic myelogenous leukemia, or C.M.L., a blood cell cancer that in the last decade has been transformed from ultimately fatal to nearly always treatable …
- —Jane E. Brody, The New York Times, 19 Jan. 2010
- Scientists have continued to hammer away at the so-called Philadelphia chromosome, a shortened chromosome 22. They now know that it results when chromosomes 9 and 22 exchange genetic material.
- —Nathan Seppa, Science News, 11 Dec. 1999