Men·kes' disease | \ ˈmeŋ-kəz-, -kə-səz- 
\
\Medical Definition of Menkes' disease
: a disorder of copper metabolism that is inherited as a recessive X-linked trait and is characterized by a deficiency of copper in the liver and of copper-containing proteins (as ceruloplasmin) which results in intellectual disability, brittle kinky hair, and typically a fatal outcome early in life
— called also Menkes' syndrome
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