Medical Definition of Mayer–Rokitansky–Küster–Hauser syndrome
: a congenital disorder that is marked especially by absence of the vagina, primary amenorrhea, absent or rudimentary uterus, and morphologically normal ovaries and external genitalia and that results from arrested development of the Müllerian ducts during early embryogenesis—called also Mayer-Rokitansky syndrome, MRKH syndrome, Müllerian agenesis
Biographical Note for mayer–rokitansky–küster–hauser syndrome
August Franz Josef Karl (1787–1865), German anatomist and physiologist. Mayer began his academic career in Bern, first as a prosector and later as a professor of anatomy, pathological anatomy, and physiology. In 1819 he accepted a similar position in Bonn and at the same time started a large medical practice. Remaining in Bonn until retirement, Mayer went on to write some 145 works, most of them in the 19th-century tradition of natural philosophy. One work of a more specific nature was an article, published in 1829, describing the congenital disorder with which his name is now associated.
Karl Freiherr von (1804–1878), Austrian pathologist. Rokitansky is credited with turning Vienna into one of the world's leading medical centers in the latter half of the 19th century. In 1834 he was appointed to the positions of prosector and extraordinary professor of pathological anatomy at Vienna General Hospital. Preeminent among descriptive pathologists, he published several noteworthy descriptions, including acute yellow atrophy of the liver (1843), spondylolisthesis and the resulting pelvic deformations (1839), and acute dilatation of the stomach (1842). Rokitansky is also remembered for his critical role in the establishment of Austria's first psychiatric clinic and for publicly supporting Ignaz Semmelweiss in his efforts to eradicate puerperal fever through the adoption of aseptic practices. Rokitansky's account of the congenital disorder associated with his name was published in 1838.
Hermann (flourished 1910), German gynecologist. Küster published in 1910 his own account of the disorder previously described by Mayer and Rokitansky.
Georges A. (flourished 1961), Swiss gynecologist. On the staff of Women's Hospital of Lucerne, Hausner in 1961 published a short article on the disorder.
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