Medical Dictionary

Lown–Ganong–Levine syndrome

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noun Lown–Gan·ong–Le·vine syndrome \ˈlau̇n-ˈgan-ˌȯŋ-lə-ˈvīn-, -ˈvēn-\

Medical Definition of Lown–Ganong–Levine syndrome

  1. :  a preexcitation syndrome characterized by atrial tachycardia together with a short P-R interval and a QRS complex of normal duration—called also LGL syndrome

Biographical Note for lown–ganong–levine syndrome


\ˈlau̇n\ play ,


(born 1921), American cardiologist. Lown enjoyed a long association with Harvard University's School of Public Health, rising to the rank of professor of cardiology and becoming director of the School's cardiovascular research laboratory. His research centered on sudden cardiac death and the identification of potential victims and on the role of neural and psychological factors leading to life-threatening disturbances of heart rhythm. He was cofounder and copresident of International Physicians for the Prevention of Nuclear War, which was awarded the Nobel Peace Prize in 1985.



William Francis

(1924–2007), American physiologist. Ganong spent the bulk of his career at the Medical School at the University of California, San Francisco, rising to the position of professor of physiology. He specialized in neuroendocrinology, investigating the interrelation between endocrine and brain function.


\lə-ˈvīn, -ˈvēn\,

Samuel Albert

(1891–1966), American cardiologist. Levine served for many years as a cardiologist at Boston's Peter Bent Brigham Hospital, which in 1965 established the Samuel Albert Levine Cardiac Center in his honor. Concurrently, he served on the faculty of Harvard Medical School, which also honored him by establishing the Samuel A. Levine Professorship of Medicine in 1954. Levine's works included Coronary Thrombosis (1929) and (with Bernard Lown) Current Concepts in Digitalis Therapy (1954). With Lown and William Ganong he coauthored the 1952 article describing the syndrome that now bears their names.

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