Medical Dictionary

Letterer-Siwe disease

noun Let·ter·er-Si·we disease \ ˈlet-ər-ər-ˈsē-və- \

medical Definition of Letterer-Siwe disease

:an acute often fatal disease of young children that is marked by proliferation of Langerhans cells and is characterized esp. by fever, anemia, hepatosplenomegaly, and a eczematous skin rash

Biographical Note for letterer-siwe disease

  • Siwe, Sture August (1897–1966), Swedish pediatrician. Siwe presented another, independent description of Letterer-Siwe disease in 1933, this time from the clinical point of view.

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