Letterer-Siwe disease

noun
Let·​ter·​er-Si·​we disease | \ ˈlet-ər-ər-ˈsē-və- How to pronounce Letterer-Siwe disease (audio) \

Medical Definition of Letterer-Siwe disease

: an acute often fatal disease of young children that is marked by proliferation of Langerhans cells and is characterized especially by fever, anemia, hepatosplenomegaly, and a eczematous skin rash

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