Medical Dictionary

Lennox-Gastaut syndrome

noun Len·nox-Gas·taut syndrome \ ˈlen-əks-gas-ˈtō- \

medical Definition of Lennox-Gastaut syndrome

: an epileptic syndrome especially of young children that is marked by several seizure types and especially tonic, atonic, and atypical absence seizures, is associated with mild to severe impairment in intellectual functioning, may be idiopathic or have an identifiable cause (as tuberous sclerosis, brain malformation, brain damage resulting from asphyxia during birth or meningitis, or metabolic disease), and is characterized between seizures by an EEG having a slow spike and wave pattern

Biographical Note for lennox-gastaut syndrome

  • Gastaut \gȧs-tō\, Henri Jean–Pascal (1915–1995), French neurologist. Gastaut served on the medical faculty of Marseilles University, eventually becoming its dean. He also acted as chief neurobiologist for public hospitals in Marseilles. From the early 1960s he was director of the Regional Center for Epileptic Children and director of the neurobiological research unit at the National Institutes of Health. His research centered on electroencephalography and epilepsy. The author of many books, monographs, and articles, he published the first description of what is now known as Lennox-Gastaut syndrome in 1957 in an article coauthored with M. Vigoroux, C. Trevisan, and H. Regis.

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