Laurence-Moon syndrome

noun
Lau·​rence-Moon syndrome | \ ˈlȯr-ən(t)s-ˈmün-\

Medical Definition of Laurence-Moon syndrome

: a genetic disorder that is a ciliopathy characterized especially by obesity, ataxia, learning disabilities, kidney abnormalities, short stature, subnormal development of the genital organs, retinitis pigmentosa, and type 2 diabetes

Note: Laurence-Moon syndrome is inherited as an autosomal recessive trait requiring that both parents pass on a copy of the defective gene on a chromosome other than a sex chromosome. Laurence-Moon syndrome was first called Laurence-Moon-Biedl syndrome until cases presenting with polydactyly and without obesity led to creation of a new disease entity, Bardet-Biedl syndrome. Because the differences between Laurence-Moon syndrome and Bardet-Biedl syndrome are not always clearly defined, some consider Laurence-Moon syndrome to be a variant form of Bardet-Biedl syndrome.

Comments on Laurence-Moon syndrome

What made you want to look up Laurence-Moon syndrome? Please tell us where you read or heard it (including the quote, if possible).

WORD OF THE DAY

a topic to which one constantly reverts

Get Word of the Day daily email!

Test Your Vocabulary

Where in the World? A Quiz

  • peter bruegel tower of babel painting
  • What language does pajama come from?
Spell It

Can you spell these 10 commonly misspelled words?

TAKE THE QUIZ
Syn City

Test Your Knowledge - and learn some interesting things along the way.

TAKE THE QUIZ
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!