Medical Definition of Lambert-Eaton syndrome
: an autoimmune disorder that is caused by impaired presynaptic release of acetylcholine at nerve synapses, that resembles myasthenia gravis, that is characterized by progressive weakness especially of the limbs, and that is often associated with a malignant condition (as small-cell lung cancer)
— called also Eaton-Lambert syndrome, Lambert-Eaton myasthenic syndrome
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