Medical Dictionary

Krabbe's disease

noun Krab·be's disease \ˈkrab-ēz-\

Medical Definition of Krabbe's disease

  1. :  a rapidly progressive demyelinating familial leukoencephalopathy with onset in infancy characterized by irritability followed by tonic convulsions, quadriplegia, blindness, deafness, dementia, and death

Biographical Note for krabbe's disease


\ˈkräb-ə\play ,

Knud H.

(1885–1961), Danish neurologist. Krabbe wrote many studies on the morphogenesis of the brain in various classes of animals. He also demonstrated that cerebrovascular malformation is the cause of many meningeal hemorrhages. He described Krabbe's disease in articles in 1913 and 1916.

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a rounded knoll or a ridge of ice

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