Du·puy·tren's contracture | \ də-ˌpwē-ˈtraⁿz- 
, -ˈpwē-trənz- \
, -ˈpwē-trənz- \Medical Definition of Dupuytren's contracture
: a condition marked by fibrosis with shortening and thickening of the palmar aponeurosis resulting in flexion contracture of the fingers into the palm of the hand
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