Medical Dictionary

Barrett's esophagus

noun Bar·rett's esophagus \ ˈbar-its-, ˈber- \
variants: also Barrett's epithelium

medical Definition of Barrett's esophagus

: metaplasia of the lower esophagus that is characterized by replacement of squamous epithelium with columnar epithelium, occurs especially as a result of chronic gastroesophageal reflux, and is associated with an increased risk for esophageal carcinoma
  • As many as 12% of the estimated 15 million GERD sufferers will develop Barrett's esophagus, and from 5% to 10% of those will go on to develop cancer.
  • —Tara Parker-PopeThe Wall Street Journal18 Oct. 2005

Biographical Note for barrett's esophagus

  • Barrett, Norman Rupert (1903–1979), British surgeon. Barrett's numerous positions included those of surgeon at King Edward VII Sanatorium, Midhurst, and at London's St. Thomas's and Royal Brompton hospitals; lecturer in surgery at the University of London; and examiner in surgery at the universities of Cambridge, Oxford, Birmingham, London, and Khartoum. He also served as editor of Thorax and contributed to several surgery textbooks.

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    of very fine texture or delicate form

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