Alport syndrome


Al·​port syndrome ˈal-ˌpȯrt- How to pronounce Alport syndrome (audio)
variants or Alport's syndrome
: a genetic disorder of the kidneys that is usually inherited as an X-linked trait, is typically more severe in males, and is characterized especially by blood in the urine, hearing loss, abnormalities of the eye, and progressive renal failure

Note: Alport syndrome is caused by mutations in genes encoding a type of collagen normally present in basement membranes.

Most victims of Alport syndrome experience progressive kidney failure, often requiring a kidney transplant or prolonged kidney dialysis.William Booth, The Washington Post

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Cite this Entry

“Alport syndrome.” Medical Dictionary, Merriam-Webster, Accessed 6 Feb. 2023.

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