Alport syndrome

noun

Al·port syndrome | \ˈal-ˌpȯrt-

variants: or Alport's syndrome

Medical Definition of Alport syndrome

: a genetic disorder of the kidneys that is usually inherited as an X-linked trait, is typically more severe in males, and is characterized especially by blood in the urine, hearing loss, abnormalities of the eye, and progressive renal failure

Note: Alport syndrome is caused by mutations in genes encoding a type of collagen normally present in basement membranes.

Most victims of Alport syndrome experience progressive kidney failure, often requiring a kidney transplant or prolonged kidney dialysis.— William Booth, The Washington Post, 8 June 1990