Medical Dictionary

AMPA

noun \ ˌā-ˌem-ˌpē-ˈā, ˈam-pə \

medical Definition of AMPA

: a synthetic amino acid C7H10N2O4 that binds selectively to a subset of glutamate receptors on neurons where the binding of glutamate results in an excitatory postsynaptic potential
  • an AMPA antagonist
  • The release of glutamate from sensory terminals evokes fast synaptic potentials in dorsal horn neurons by activating the AMPA-type glutamate receptors.
  • —Allan I. Basbaum and Thomas M. Jessell, in Principles of Neural Science, 4th edition2000
; also : the subset of receptors to which AMPA binds
  • Glutamate binds to two types of receptor on the postsynaptic neuron, called AMPA and NMDA.
  • New Scientist17 May 2003

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