Medical Dictionary


noun \ˌā-ˌem-ˌpē-ˈā, ˈam-pə\

Medical Definition of AMPA

  1. :  a synthetic amino acid C7H10N2O4 that binds selectively to a subset of glutamate receptors on neurons where the binding of glutamate results in an excitatory postsynaptic potential an AMPA antagonist The release of glutamate from sensory terminals evokes fast synaptic potentials in dorsal horn neurons by activating the AMPA-type glutamate receptors.—Allan I. Basbaum and Thomas M. Jessell, in Principles of Neural Science, 4th edition, 2000; also :  the subset of receptors to which AMPA binds Glutamate binds to two types of receptor on the postsynaptic neuron, called AMPA and NMDA.—New Scientist, 17 May 2003

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