mental illness

noun

variants or mental disorder or less commonly mental disease

: any of a broad range of medical conditions (such as major depression, schizophrenia, obsessive compulsive disorder, or panic disorder) that are marked primarily by sufficient disorganization of personality, mind, or emotions to impair normal psychological functioning and cause marked distress or disability and that are typically associated with a disruption in normal thinking, feeling, mood, behavior, interpersonal interactions, or daily functioning

mentally ill adjective

Examples of mental illness in a Sentence

Recent Examples on the Web

The shooting sparked outrage, and changes to official practices around law enforcement and people with mental illnesses. —JSTOR Daily, 5 Nov. 2025

The killing of Massey, a mother of two who had long struggled with mental illness, touched off a wave of demonstrations and nationwide calls for police reform. —Christopher Cann, USA Today, 29 Oct. 2025

In 18th century Europe, trepanation was used to treat mental illness and epilepsy. —Lauren Liebhaber, Miami Herald, 29 Oct. 2025

Nearly 80% of California’s homeless also suffer from the brain diseases of addiction and mental illness, yet programs that require sobriety and not eligible for state funding. —Michele Steeb, Oc Register, 29 Oct. 2025

Word History

First Known Use

1724, in the meaning defined above

Rhymes for mental illness

• stillness

Kids Definition

mental illness

noun

variants or mental disorder

: a medical condition that is marked by a mild to severe disturbance in the way a person thinks, feels, or acts and is usually accompanied by distress and problems functioning in daily activities or interacting with others

mentally ill adjective

Medical Definition

mental illness

noun

variants or mental disorder also mental disease

: any of a broad range of medical conditions (such as major depression, schizophrenia, obsessive compulsive disorder, or panic disorder) that are marked primarily by sufficient disorganization of personality, mind, or emotions to impair normal psychological functioning and cause marked distress or disability and that are typically associated with a disruption in normal thinking, feeling, mood, behavior, interpersonal interactions, or daily functioning

Some homeless families are also hindered by substance abuse and mental illness.

—Ellen L. Bassuk, Scientific American

Catatonia is usually an expression of mental disorders like bipolar disorder or schizophrenia, but it could also come from other medical problems, such as a brain tumor.

—Forrest Wickman, The Pittsburgh Post-Gazette

… mental diseases such as schizophrenia and manic depression may either involve more than one gene or may result from a complex mix of genetic predisposition and environmental rotten luck.

—Natalie Angier, The New York Times Book Review

mentally ill adjective

mentally ill patients

Mental health workers … perform a wide variety of therapeutic, supportive, and preventative functions for persons who are mentally ill and developmentally disabled.

—Barbara M. Swanson, Careers in Health Care

Legal Definition

mental illness

noun

mental ill·​ness

1

: mental disease

2

: a mental condition marked primarily by sufficient disorganization of personality, mind, and emotions to seriously impair the normal psychological and often social functioning of the individual

called also mental disorder