what's up with

idiom

Definition of what's up with

informal
1 : what is the reason for (something) He told me to go away. What's up with that?
2 : what is wrong with (someone or something) What's up with you? You look upset. I can't figure out what's up with this computer.

More from Merriam-Webster on what's up with

Britannica English: Translation of what's up with for Arabic Speakers

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