von Willebrand factor

noun

Definition of von Willebrand factor 

: a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease

called also VW factor

Note: Von Willebrand factor is synthesized in endothelial cells of blood vessels and in megakaryocytes of bone marrow.

First Known Use of von Willebrand factor

1970, in the meaning defined above

History and Etymology for von Willebrand factor

after Erik Adolf von Willebrand †1949 Finnish physician

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The first known use of von Willebrand factor was in 1970

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von Willebrand factor

noun
von Wil·le·brand factor | \vän-ˈvil-ə-ˌbränt- \

Medical Definition of von Willebrand factor 

: a large glycoprotein clotting factor circulating in blood plasma that mediates platelet adhesion to collagen at sites of vascular injury, that binds to and protects factor VIII from degradation, and that is deficient or defective in individuals affected with von Willebrand disease Patients are deficient in the von Willebrand factor, one of the many blood-clotting proteins.— Paul G. Donohue, The Springfield (Massachusetts) Union-News, 6 July 1994

Note: Von Willebrand factor is synthesized in endothelial cells of blood vessels and in megakaryocytes of bone marrow.

called also VW factor

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