vin·​cris·​tine (ˌ)vin-ˈkri-ˌstēn How to pronounce vincristine (audio)
: an alkaloid C46H56N4O10 from the rosy periwinkle used especially in the form of its sulfate to treat some human neoplastic diseases (such as acute leukemia)

Examples of vincristine in a Sentence

Recent Examples on the Web Later that month, another drug shortage threatened to delay Abby’s treatment, but for a chemotherapy drug that’s a mainstay for many types of pediatric cancer treatment: vincristine. Brenda Goodman, CNN, 29 Dec. 2022 Medications like chemotherapy drugs vincristine (Marqibo), paclitaxel (Abraxane) can also exacerbate symptoms, the Mayo Clinic says. Korin Miller,, 28 Sep. 2021 The average sales price for a vial of vincristine is about $5, according to the Children’s Oncology Group letter. Todd Ackerman,, 25 Oct. 2019 Until earlier this year, there were two suppliers of vincristine: Pfizer and Teva Pharmaceutical Industries. Roni Caryn Rabin, New York Times, 14 Oct. 2019 In the case of vincristine, for example, the medication was only made by two companies. NBC News, 2 Nov. 2019 The Food and Drug Administration, whose website lists vincristine as currently in shortage, says deliveries should resume later this month. Todd Ackerman,, 25 Oct. 2019 When treated with carboplatin and vincristine, the two chemotherapy drugs Zahler had recommended, 70 percent of patients saw their tumors shrink or stabilize, the doctor said. Andrea Simakis,, 13 May 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'vincristine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


vinca + Latin crista crest + English -ine entry 2 — more at crest

First Known Use

circa 1962, in the meaning defined above

Time Traveler
The first known use of vincristine was circa 1962

Dictionary Entries Near vincristine

Cite this Entry

“Vincristine.” Dictionary, Merriam-Webster, Accessed 20 Jul. 2024.

Medical Definition


vin·​cris·​tine (ˈ)vin-ˈkris-ˌtēn How to pronounce vincristine (audio)
: an alkaloid that is obtained from the rosy periwinkle and that is used especially in the form of its sulfate C46H56N4O10·H2SO4 to treat some human neoplastic diseases (as acute leukemia)

called also leurocristine

see oncovin

More from Merriam-Webster on vincristine

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!