va·​line ˈva-ˌlēn How to pronounce valine (audio) ˈvā- How to pronounce valine (audio)
: a crystalline essential amino acid C5H11NO2 that is one of the building blocks of plant and animal proteins

Examples of valine in a Sentence

Recent Examples on the Web Challenging workouts and proper fueling will be your best muscle builders. BCAAs BCAAs contain three essential amino acids: leucine, isoleucine, and valine. Donavyn Coffey, TIME, 1 Apr. 2024 The switch of an A to a T in the genetic code for hemoglobin results in a hemoglobin protein with a valine instead of a glutamic acid at the sixth amino acid position. Beth Mole, Ars Technica, 8 Dec. 2023 High-quality protein is any protein that contains all of the nine essential amino acids (histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine) that our bodies don’t make on their own. USA TODAY, 2 July 2023 These include leucine, valine, isoleucine and a handful of other amino acids your body cannot naturally produce. Dallas News, 15 Feb. 2022 Three substitutions were identified: L50F (in which leucine at position 50 is substituted by phenylalanine), E166A or E166V (in which glutamic acid at position 166 is substituted by alanine or valine) and L167F (in which leucine at position 167 is substituted by phenylalanine). William A. Haseltine, Forbes, 9 June 2022 Leucine, like valine and isoleucine, is a branched-chain amino acid. Dr. Keith Roach, oregonlive, 28 Nov. 2022 Branched-chain amino acids (BCAAs) are a class of three important amino acids known as leucine, isoleucine, and valine. Amber Smith, Discover Magazine, 22 Dec. 2022 Every scoop of Plant JYM Vegan Protein Powder contains 24 grams of protein and five grams of leucine, isoleucine and valine, stacked at the recommend 2:1:1 ratio. Dallas News, 15 Feb. 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'valine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


borrowed from German Valin, from Valeriansäure valeric acid + -in -ine entry 2

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of valine was in 1907

Dictionary Entries Near valine

Cite this Entry

“Valine.” Dictionary, Merriam-Webster, Accessed 16 Jul. 2024.

Medical Definition


: a crystalline essential amino acid C5H11NO2 that occurs especially in fibrous proteins
abbreviation Val

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