tryptamine

noun

trypt·​amine ˈtrip-tə-ˌmēn How to pronounce tryptamine (audio)
: a crystalline amine C10H12N2 derived from tryptophan

Examples of tryptamine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The study was published Sept. 11 in JAMA Network Open, showing that edibles labeled as containing psilocybin did not in fact contain the ingredient, and instead contained muscimol, synthetic tryptamines, or other adulterants. Benjamin Adams, Forbes.com, 16 Sep. 2025 So, not only was ayahuasca powered by DMT, but was also, as William Burroughs had speculated, a true pharmacological technology, exploiting the synergistic interaction between the constituent harmala and tryptamine alkaloids. Literary Hub, 16 July 2025 Additionally, Colorado’s law bans manufacturers from using synthetic tryptamines, such as 4-acO-DMT, and requires edibles to be tested for synthetics before they are distributed. Tiney Ricciardi, The Denver Post, 16 Aug. 2024 The results do not include an analysis of tryptamines or synthetic drugs. Christine Ricciardi, The Mercury News, 9 Aug. 2024 Some products sold as mushroom chocolates or candies instead contain a synthetic psychoactive tryptamine called 4-acetoxy-dimethyltryptamine, or 4-AcO-DMT. Keri Blakinger, Los Angeles Times, 9 Aug. 2024

Word History

Etymology

trypt(ophan) + amine

First Known Use

1929, in the meaning defined above

Time Traveler
The first known use of tryptamine was in 1929

Browse Nearby Words

Cite this Entry

“Tryptamine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tryptamine. Accessed 22 Jan. 2026.

Medical Definition

tryptamine

noun
trypt·​amine ˈtrip-tə-ˌmēn How to pronounce tryptamine (audio)
: a crystalline amine C10H12N2 derived from tryptophan
also : any of various substituted derivatives of this amine of which some are significantly hallucinogenic or neurotoxic
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!