troponin

noun

tro·​po·​nin ˈtrō-pə-nən How to pronounce troponin (audio)
ˈträ-,
-ˌnin
: a protein of muscle that together with tropomyosin forms a regulatory protein complex controlling the interaction of actin and myosin and that when combined with calcium ions permits muscular contraction

Example Sentences

Recent Examples on the Web According to the International Federation of Clinical Chemistry and Laboratory Medicine, one key characteristic of a hs-cTn assay is the ability to detect troponin in ≥50% of healthy individuals7. Christos Varounis, Scientific American, 3 Nov. 2021 Yet there was some drama earlier this week after a pre-draft physical revealed unusually high troponin levels in Paye's blood, according to NFL.com's Ian Rapoport. Orion Sang, Detroit Free Press, 30 Apr. 2021 Fifth, dose-response gradient, as higher troponin levels are associated with higher CV risk. Christos Varounis, Scientific American, 3 Nov. 2021 The blood test Erickson recommends measures troponin proteins, which are normally found in the heart muscle but released into the bloodstream when the heart is injured. Stephanie Innes, USA TODAY, 22 Sep. 2020 Several studies have now shown that roughly 10 to 30 percent of hospitalized COVID-19 patients had high levels of troponin—a protein released into the blood when the heart’s muscle cells are damaged. Ed Yong, The Atlantic, 21 Sep. 2020 Ideally, such athletes should undergo cardiac imaging, plus a blood test for troponin -- which may indicate heart-muscle damage -- to rule out ongoing myocardial damage that would predispose the heart to additional strain, Jennings said. Jason Gale, Bloomberg.com, 8 Sep. 2020 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'troponin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

Etymology

by shortening & alteration from tropomyosin

Note: The name was apparently first used in print in a letter by the Japanese biochemist Setsuro Ebashi (1922-2006) and coworker Ayako Kodama, "Interaction of Troponin with F-Actin in the Presence of Tropomyosin," Journal of Biochemistry (Japanese Biochemical Society), vol. 59, issue 4 (April, 1966), p. 425.

First Known Use

1966, in the meaning defined above

Time Traveler
The first known use of troponin was in 1966

Dictionary Entries Near troponin

Cite this Entry

“Troponin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/troponin. Accessed 30 Nov. 2022.

Medical Definition

troponin

noun

tro·​po·​nin ˈtrōp-ə-nən How to pronounce troponin (audio) ˈträp- How to pronounce troponin (audio)
-ˌnin
: a protein of muscle that together with tropomyosin forms a regulatory protein complex controlling the interaction of actin and myosin and that when combined with calcium ions permits muscular contraction

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