tricyclic antidepressant

noun

: any of a group of antidepressant drugs (such as imipramine and amitriptyline) that contain three fused benzene rings, potentiate the action of catecholamines (such as norepinephrine and serotonin) by inhibiting their uptake by nerve endings, and do not inhibit the action of monoamine oxidase

called also tricyclic

Examples of tricyclic antidepressant in a Sentence

Recent Examples on the Web And in that year, a type of medication, a tricyclic antidepressant, was first found to be effective for treating symptoms of depression. Steven Strogatz, Quanta Magazine, 23 May 2024 Some medications that interact with these supplements include: tricyclic antidepressants (Amitriptyline, Doxepin, Imipramine) diabetes medications (glyburide and metformin) carbamazepine cholesterol-lowering medications (Colestipol and cholestyramine) Sugar alcohols may cause diarrhea and bloating. Suzie Finkel Ms, Rd, Cdn, Health, 26 May 2024 Fiber supplements may interact with diabetes medications and interfere with your body’s ability to absorb certain medications, such as tricyclic antidepressants, carbamazepine, digoxin, lithium, or diabetes medications. Erika Prouty, Verywell Health, 11 Apr. 2024 Drugs that may cause a problem include barbiturates, benzodiazepines, chlorpromazine, reserpine, and tricyclic antidepressants. Katie Wiseman, The Indianapolis Star, 19 Jan. 2024 Taking vitamin E interferes with the absorption of the following drugs: tricyclic antidepressants, antipsychotic medication, Thorazine, and beta blockers. Allison Futterman, Discover Magazine, 16 Feb. 2024 Healthcare providers are also now recommending very low-dose tricyclic antidepressants (TCAs) such as amitryptiline for chronic pain, or anti-epilepsy drugs (AEDs) such as Neurontin (gabapentin) or Lyrica (pregabalin), which work by decreasing the frequency of nerve pain signals sent to the brain. Elizabeth Woolley, Verywell Health, 28 May 2023 Due to its molecular structure, amitriptyline is described as a tricyclic antidepressant. Verywell Health, 14 Feb. 2023 There are a lot of options out there, including beta blockers (which reduce your blood pressure) and tricyclic antidepressants (these affect your levels of serotonin and other brain chemicals). Korin Miller, SELF, 3 Aug. 2018

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Word History

First Known Use

1966, in the meaning defined above

Time Traveler
The first known use of tricyclic antidepressant was in 1966

Dictionary Entries Near tricyclic antidepressant

Cite this Entry

“Tricyclic antidepressant.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tricyclic%20antidepressant. Accessed 14 Jun. 2024.

Medical Definition

tricyclic antidepressant

noun
: any of a group of antidepressant drugs (as imipramine, amitriptyline, desipramine, and nortriptyline) that contain three fused benzene rings, that potentiate the action of catecholamines (as norepinephrine and serotonin) by inhibiting their uptake by nerve endings, and that do not inhibit the action of monoamine oxidase
Last Updated: - Updated example sentences
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