traz·​o·​done ˈtra-zə-ˌdōn How to pronounce trazodone (audio)
: an antidepressant drug C19H22ClN5O administered in the form of its hydrochloride

Example Sentences

Recent Examples on the Web Another drug Clancy was prescribed called trazodone (often used in small doses for insomnia), shares many properties with SSRIs but is in a separate class of drugs called serotonin receptor antagonists and reuptake inhibitors, or SARIs. Jessica Bartlett,, 3 Feb. 2023 Prescription medications: These include trazodone, zolpidem (Ambien), eszopiclone (Lunesta), and ramelteon (Rozerem). Amber Smith, Discover Magazine, 12 Oct. 2022 Gil was taking the antidepressant trazodone, medical records show. Kelly Davis, San Diego Union-Tribune, 4 Apr. 2022 Although non-prescription melatonin is by far the most popular, some children are prescribed epilepsy drugs, sedatives, alpha agonists such as clonidine or antidepressants such as trazodone, depending on the nature of their problem. Claudia Wallis, Scientific American, 18 Nov. 2017 Stacy Williams dialed 911 on Jan. 26 in search of a catheter for her 14-year-old grandson Jacah, a survivor of shaken baby syndrome, who had been administered two doses of trazodone and was asleep for an extended time, as expected. Kayla Rivas, Fox News, 22 July 2021 AvKARE, a healthcare firm based out of Pulaski, Tennessee, on Tuesday announced a recall of its generic sildenafil, the active ingredient in Viagra, and trazodone, an antidepressant and sleep aid. Joshua Bote, USA TODAY, 10 Dec. 2020 Unintentional intake of trazodone can results in sedation, dizziness, constipation and blurred vision. Jen Christensen, CNN, 10 Dec. 2020 Though the recall itself is relatively small — a single lot of each medication, affecting only 100 bottles of sildenafil and 1,000 bottles of trazodone — patients who wrongly take either medication could face severe health risks. Joshua Bote, USA TODAY, 10 Dec. 2020 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'trazodone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History


perhaps from International Scientific Vocabulary triazo azido + pyridine + -one

First Known Use

1971, in the meaning defined above

Time Traveler
The first known use of trazodone was in 1971

Dictionary Entries Near trazodone

Cite this Entry

“Trazodone.” Dictionary, Merriam-Webster, Accessed 26 Mar. 2023.

Medical Definition


traz·​o·​done ˈtraz-ə-ˌdōn How to pronounce trazodone (audio)
: an antidepressant drug that is administered in the form of its hydrochloride C19H22ClN5O·HCl and inhibits the uptake of serotonin by the brain

More from Merriam-Webster on trazodone

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