transcription factor

noun

: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription

Example Sentences

Recent Examples on the Web Scientists have speculated that the activation of a transcription factor called STAT3 can induce advanced wet macular degeneration. William A. Haseltine, Forbes, 24 Jan. 2023 The other pathway suppresses a transcription factor that seems to promote a longer life span. Viviane Callier, Quanta Magazine, 10 Jan. 2023 One example is phage phi29, which exploits its host’s transcription factor to detect when the bacterium is getting ready to generate a spore, or a kind of bacterial egg capable of surviving extreme environments. Ivan Erill-university Of Maryland, Discover Magazine, 18 Oct. 2022 This protein, or transcription factor, allows researchers to better control the T cell by inducing it to produce a specific protein. Gregory Allen, The Conversation, 15 Dec. 2022 Some of his recent work has involved a transcription factor called HIF-2. Markham Heid, Time, 26 Dec. 2022 The mutation may be in a transcription factor that regulates the activity of EPAS1. Razib Khan, Discover Magazine, 1 July 2010 This transcription factor upregulates the activity of 345 genes, most of them known to respond to salt, drought, and cold stresses. Diana Gitig, Ars Technica, 29 July 2022 This cascade of reactions leads to the activation of the transcription factor NFkB. NFkB induces several cell defenses, including inflammation. William A. Haseltine, Forbes, 25 Apr. 2022 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'transcription factor.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1969, in the meaning defined above

Time Traveler
The first known use of transcription factor was in 1969

Dictionary Entries Near transcription factor

Cite this Entry

“Transcription factor.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/transcription%20factor. Accessed 3 Feb. 2023.

Medical Definition

transcription factor

noun
: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription

More from Merriam-Webster on transcription factor

Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!


Words Named After People

  • name tags
  • Namesake of the leotard, Jules Léotard had what profession?
Spell It

Hear a word and type it out. How many can you get right?

TAKE THE QUIZ
Solve today's spelling word game by finding as many words as you can with using just 7 letters. Longer words score more points.

Can you make 12 words with 7 letters?

PLAY