transcription factor

noun

Definition of transcription factor

: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription

Examples of transcription factor in a Sentence

Recent Examples on the Web

By injecting certain proteins (called transcription factors) involved in development directly into the brain, Götz and her team in Munich have figured out how to alter the function of astrocytes after an injury. Jacqueline Detwiler, Popular Mechanics, "The Heroes of Science Who Are Unlocking the Brain," 3 Oct. 2018 That doesn’t mean that fifteen years from now doctors will be able to prescribe a course of transcription factors to cure PSP. Jacqueline Detwiler, Popular Mechanics, "The Heroes of Science Who Are Unlocking the Brain," 3 Oct. 2018 But its promoters—the regulatory DNA that interacts with transcription factors—were much shorter and simpler than in animals, the groups reported on 19 May 2016 in Cell, suggesting less sophisticated regulation. Elizabeth Pennisi, Science | AAAS, "The momentous transition to multicellular life may not have been so hard after all," 28 June 2018 Like all transcription factors, STAT3 functions by binding specific bits of DNA to control gene expression. Beth Mole, Ars Technica, "Scientists use caffeine to control genes—and treat diabetic mice with coffee," 20 June 2018 The most finely tuned of these was a system that used a regulator called EpoR, which becomes active when its dimerizes and triggers a transcription factor, called STAT3. Beth Mole, Ars Technica, "Scientists use caffeine to control genes—and treat diabetic mice with coffee," 20 June 2018 And although the activity of key transcription factor genes was similar in common cell types, the activity of other genes in some cell types differed more than the researchers expected between the two species. Elizabeth Pennisi, Science | AAAS, "How one cell gives rise to an entire body," 26 Apr. 2018 Adding seven transcription factors — proteins that switch on genes — the team then converted the IPSCs into immature HSC-like cells. Linda Marsa, Discover Magazine, "Making Blood Cells in the Laboratory," 1 Feb. 2018 The Weill Cornell researchers’ process was more direct: Four transcription factors prompted adult mouse endothelial cells, which line the inside of blood vessels, to turn into HSCs. Linda Marsa, Discover Magazine, "Making Blood Cells in the Laboratory," 1 Feb. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'transcription factor.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of transcription factor

1972, in the meaning defined above

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The first known use of transcription factor was in 1972

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More Definitions for transcription factor

transcription factor

noun

Medical Definition of transcription factor

: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription

More from Merriam-Webster on transcription factor

Britannica.com: Encyclopedia article about transcription factor

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