transcription factor


Definition of transcription factor

: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription

Examples of transcription factor in a Sentence

Recent Examples on the Web Babonis found that a single transcription factor was enough to stop immature cells from developing as neurons and turn them into stinging cells instead, complete with a barbed, coiled filament for capturing prey. Quanta Magazine, 16 Aug. 2021 The snapdragon gene in Martin’s tomato, for instance, is known as a transcription factor: essentially, a kind of volume knob that regulates how much of something a particular gene will produce. New York Times, 20 July 2021 Frazer wanted to know how a heart-specific transcription factor called NKX2-5 influenced those traits. Elizabeth Pennisi, Science | AAAS, 10 Sep. 2020 Semenza discovered a protein complex called hypoxia-inducible factor (HIF), which is composed of two transcription factors—proteins that control the transcription of DNA into RNA—called HIF-1α and ARNT. Tanya Lewis, Scientific American, 7 Oct. 2019 In 1952, well before developmental biologists spoke in terms of Hox genes and transcription factors, or even understood DNA’s structure, Alan Turing had an idea. Quanta Magazine, 2 Jan. 2019 Scientists achieve this transformation by bathing the stem cells in a solution containing the right cocktail of transcription factors, molecules that guide fetal development by regulating how genes are turned on or off. Bret Stetka, Scientific American, 29 Aug. 2019 In 1988, Ueli Schibler, now a professor of molecular biology at the University of Geneva, was studying transcription factors, cellular actors that control the transcription of genes into proteins. Quanta Magazine, 15 Sep. 2015 When Wuarin performed the isolation, the transcription factor had failed to appear. Quanta Magazine, 15 Sep. 2015

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'transcription factor.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of transcription factor

1972, in the meaning defined above

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The first known use of transcription factor was in 1972

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Last Updated

26 Aug 2021

Cite this Entry

“Transcription factor.” Dictionary, Merriam-Webster, Accessed 16 Oct. 2021.

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More Definitions for transcription factor

transcription factor


Medical Definition of transcription factor

: any of various proteins that bind to DNA and play a role in the regulation of gene expression by promoting transcription

More from Merriam-Webster on transcription factor Encyclopedia article about transcription factor


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