tirzepatide

noun

tir·​zep·​a·​tide tər-ˈze-pə-ˌtīd 

plural tirzepatides

: a drug C₂₂₅H₃₄₈N₄₈O₆₈ that selectively binds to and activates cell receptors for glucagon-like peptide-1 and gastric inhibitory polypeptide acting to stimulate insulin secretion, decrease glucagon secretion, and delay gastric emptying and that is administered by injection for the management of type 2 diabetes or for the promotion of weight loss in obese patients or in overweight patients with a comorbidity

… tirzepatide and semaglutide work similarly to reduce appetite and improve blood sugar control, but differ in their hormone targets, weight-loss results, and dosing. … Tirzepatide works on more than one appetite-related pathway, which may explain why it leads to greater weight loss for some people.

—Kweli I. Wright

Note: Tirzepatide is marketed under the trademarks Mounjaro and Zepbound.

Word History

Etymology

tirzepa- (of undetermined origin) + (pep)tide

First Known Use

2018, in the meaning defined above

Rhymes for tirzepatide

• acetamide
• acetonide
• acidified
• antimonide
• beatified
• benzaldehyde
• borohydride
• chalcogenide
• commodified
• decalcified
• declassified
• disaccharide

Medical Definition

tirzepatide

noun

tir·​zep·​a·​tide tər-ˈzep-ə-ˌtīd 

: a drug C₂₂₅H₃₄₈N₄₈O₆₈ that selectively binds to and activates cell receptors for glucagon-like peptide 1 and gastric inhibitory polypeptide acting to stimulate insulin secretion, decrease glucagon secretion, and delay gastric emptying and that is administered by injection for the management of type 2 diabetes or for the promotion of weight loss in obese patients or in overweight patients with a comorbidity

Note: Tirzepatide is marketed under the trademarks Mounjaro and Zepbound.