thrombin

noun

throm·​bin ˈthräm-bən How to pronounce thrombin (audio)
: a proteolytic enzyme that is formed from prothrombin and facilitates the clotting of blood by catalyzing conversion of fibrinogen to fibrin

Examples of thrombin in a Sentence

Recent Examples on the Web At the same time, the body increases production of thrombin, a clotting agent in the blood. Kaitlin Sullivan, NBC News, 27 Sep. 2023 Blood converts to fibrin by thrombin in the early stages of clot formation, causing the platelets to activate faster. Kaitlin Clark, Allure, 1 Nov. 2021 His team has started such a study and going forward will test varying doses of either the classic blood thinner heparin or one of the newer, oral anticoagulant drugs such as dabigatran, a direct thrombin inhibitor. Maggie Fox, CNN, 6 May 2020 Our analysis of the molecular composition of these stitch points showed that one of these molecules, neurofascin 155, has a site that can be cleaved by a specific enzyme, thrombin, to thin the myelin. R. Douglas Fields, Scientific American, 12 Mar. 2020 The study published in the journal Nature Biotechnology uses nanotechnology to deliver thrombin, an enzyme that helps blood to clot. Brett Molina, USA TODAY, 13 Feb. 2018 The thrombin was placed using DNA origami, a process where DNA is folded into specific shapes. Brett Molina, USA TODAY, 13 Feb. 2018 In this complex process known as a coagulation cascade, an enzyme in your blood called thrombin allows a protein called fibrinogen to form a net-like structure that hardens and contracts. Korin Miller, SELF, 15 Dec. 2017 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'thrombin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

International Scientific Vocabulary

First Known Use

1897, in the meaning defined above

Time Traveler
The first known use of thrombin was in 1897

Dictionary Entries Near thrombin

Cite this Entry

“Thrombin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/thrombin. Accessed 22 Feb. 2024.

Medical Definition

thrombin

noun
throm·​bin ˈthräm-bən How to pronounce thrombin (audio)
: a proteolytic enzyme formed from prothrombin that facilitates the clotting of blood by catalyzing conversion of fibrinogen to fibrin and that is used in the form of a powder as a topical hemostatic

called also thrombase

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