: either of two physiologically active isomers C21H30O2 from hemp plant resin
especially : one that is the chief intoxicant in marijuana
When a person tokes, eats or vapes cannabis, a wave of THC, or tetrahydrocannabinol, washes into the brain. Laura Sanders
THC, the main chemical component of marijuana, has been shown to reduce nausea and increase appetite in chemotherapy patients. Andrew Weil
THC disappears from blood quickly as it is absorbed in the brain, making blood tests a more reliable measure of recent use but not a great correlate of impairment. Eliza Gray

Examples of THC in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Yes, products that meet the state’s THC limit and follow packaging, labeling and testing requirements can still be sold in Texas. Tiffani Jackson, Fort Worth Star-Telegram, 13 Mar. 2026 However, a recent Milwaukee Journal Sentinel investigation found that many of these hemp products contain THC above the federal limit. Gina Lee Castro, jsonline.com, 13 Mar. 2026 Prosecutors say his blood tested positive for THC (10 nanograms per milliliter of blood). Amanda Lee Myers, USA Today, 10 Mar. 2026 The ordinance will create a new inspection and licensing program for retailers selling tobacco, kratom, and other THC products, with the goal of reducing youth access and usage and protecting kids from tobacco products. Ashley Portillo, CBS News, 10 Mar. 2026 See All Example Sentences for THC

Word History

Etymology

tetrahydrocannabinol

First Known Use

1967, in the meaning defined above

Time Traveler
The first known use of THC was in 1967

Browse Nearby Words

Cite this Entry

“THC.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/THC. Accessed 15 Mar. 2026.

Medical Definition

: either of two physiologically active isomers C21H30O2 that occur naturally in hemp plant resin or are synthetically prepared:
a
: one that is the chief intoxicant in marijuana and is used medicinally

called also delta-9-tetrahydrocannabinol, delta-9-THC

see dronabinol
b
: one that is present in marijuana only in minute quantities

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