Definition of thalidomide
: a drug C13H10N2O4 that was formerly used as a sedative and is now used as an immunomodulatory agent especially in the treatment of leprosy and multiple myeloma and that is known to cause malformations of infants born to mothers using it during pregnancy
Recent Examples of thalidomide from the Web
Because Congress was in a rush to respond to the thalidomide tragedy in the early 1960s, when the babies of some women who took the morning-sickness drug were left with permanent birth defects.
Kelsey’s wide-ranging experience in the 1930s, ’40s and ’50s would serve her well in the 1960s to recognize the threat of thalidomide.
But Kelsey’s body of work goes well beyond thalidomide.
By 1962, reeling from news of birth defects caused by a drug called thalidomide, Congress amended the Food, Drug, and Cosmetic Act, requiring trials to include enhanced safety testing and placebo control groups.
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Origin and Etymology of thalidomide
phthalic acid + -id- (from imide) + -o- + imide
First Known Use: 1958See Words from the same year
Medical Definition of thalidomide
: a sedative, hypnotic, and antiemetic drug C13H10N2O4 that was formerly used chiefly in Europe during the late 1950s and early 1960s especially to treat morning sickness but was soon withdrawn after being shown to cause serious malformations (as missing or severely shortened arms and legs) in infants born to mothers using it during the first trimester of pregnancy and that is now used as an immunomodulatory agent chiefly in the treatment of cutaneous complications of leprosy and in combination with dexamethasone in the treatment of multiple myeloma
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