syphilis

noun

syph·​i·​lis ˈsi-f(ə-)ləs How to pronounce syphilis (audio)
: a chronic contagious usually venereal and often congenital disease caused by a spirochete (Treponema pallidum) and if left untreated producing chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years compare primary syphilis, secondary syphilis, tertiary syphilis
syphilitic adjective or noun

Examples of syphilis in a Sentence

Recent Examples on the Web
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The decades-long study, performed by the U.S. Public Health Service and the Centers for Disease Control and Prevention, observed the long-term effects of syphilis in hundreds of impoverished Black men between 1932 and 1972. Alexa Jurado, Journal Sentinel, 27 Dec. 2022 The medical field is working to rebuild trust with communities that have been wronged by events such as the Tuskegee syphilis experiments and the treatment of Henrietta Lacks. Donovan J. Thomas, ajc, 10 Dec. 2022 Even as recently as the 1970s U.S. physicians were conducting trials withholding treatment from African American men with syphilis, watching as hundreds of men went blind, died and passed on the disease to their spouses and children. Dr. Nicole Farha, ABC News, 10 Nov. 2022 Then his father told him about the Tuskegee experiment, in which Black men were deliberately infected with syphilis without consent. Michael O'Sullivan, Washington Post, 10 Nov. 2022 See All Example Sentences for syphilis

Word History

Etymology

New Latin, from Syphilus, hero of the poem Syphilis sive Morbus Gallicus (Syphilis or the French disease) (1530) by Girolamo Fracastoro †1553 Italian poet and physician

First Known Use

1653, in the meaning defined above

Time Traveler
The first known use of syphilis was in 1653

Browse Nearby Words

Cite this Entry

“Syphilis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/syphilis. Accessed 9 Sep. 2025.

Kids Definition

syphilis

noun
syph·​i·​lis ˈsif-(ə-)ləs How to pronounce syphilis (audio)
: a venereal disease that is caused by a spirochete and if left untreated is marked by a series of three stages extending over many years
syphilitic adjective or noun

Medical Definition

syphilis

noun
syph·​i·​lis ˈsif-(ə-)ləs How to pronounce syphilis (audio)
: a chronic contagious usually venereal and often congenital disease that is caused by a spirochete of the genus Treponema (T. pallidum) and if left untreated produces chancres, rashes, and systemic lesions in a clinical course with three stages continued over many years

called also lues

see primary syphilis, secondary syphilis, tertiary syphilis

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