sub·​til·​i·​sin ˌsəb-ˈti-lə-sən How to pronounce subtilisin (audio)
: a protease secreted by a soil bacillus (Bacillus amyloliquefaciens)

Examples of subtilisin in a Sentence

Recent Examples on the Web With these steps in place, Arnold was able to work with with a protein-digesting enzyme known as subtilisin. David Grossman, Popular Mechanics, 3 Oct. 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'subtilisin.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


New Latin subtilis, specific epithet of Bacillus subtilis, species to which Bacillus amyloliquefaciens was once thought to belong

First Known Use

1953, in the meaning defined above

Time Traveler
The first known use of subtilisin was in 1953

Dictionary Entries Near subtilisin

Cite this Entry

“Subtilisin.” Dictionary, Merriam-Webster, Accessed 20 Apr. 2024.

Medical Definition


sub·​til·​i·​sin ˌsəb-ˈtil-ə-sən How to pronounce subtilisin (audio)
: an extracellular protease that is secreted by a soil bacterium of the genus Bacillus (B. amyloliquefaciens) and has various commercial uses (as in laundry detergents)
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