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First Known Use of spherule
1665
Medical Dictionary
medical Definition of spherule
: a thick-walled spherical structure enclosing endospores and occurring in the parasitic form of fungi of the genus Coccidioides
- Histopathological examination revealed spherules that were consistent with coccidioides species and focal organizing pneumonia with eosinophilia.
- —Holenarasipur R. Vikram et al., The New England Journal of Medicine, 2 June 2011
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