spherule

noun
spher·​ule | \ˈsfir-ül, ˈsfer-, -ˌyül \

Definition of spherule 

: a little sphere or spherical body

First Known Use of spherule

1665, in the meaning defined above

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The first known use of spherule was in 1665

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spherule

noun
spher·​ule | \ˈsfir-ül, ˈsfer-, -ˌyül \

Medical Definition of spherule 

: a thick-walled spherical structure enclosing endospores and occurring in the parasitic form of fungi of the genus Coccidioides Histopathological examination revealed spherules that were consistent with coccidioides species and focal organizing pneumonia with eosinophilia.— Holenarasipur R. Vikram et al., The New England Journal of Medicine, 2 June 2011

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