sickle cell


Definition of sickle cell

: an abnormal red blood cell of crescent shape

Examples of sickle cell in a Sentence

Recent Examples on the Web The agency has cleared Oxbryta to treat the blood disorder sickle cell disease. Sy Mukherjee, Fortune, "American Life Expectancy Is Still Dropping. But Why?," 26 Nov. 2019 In recent years Hydroxyurea has been the standard-of-care drug for the treatment of sickle cell disease’s pain crisis. Paul Adepoju, Quartz Africa, "A new Sickle cell disease drug holds much promise but most sufferers won’t be able to afford it," 26 Nov. 2019 Kenya Evans said the Navy discovered that her daughter Kierra, 20, possessed the sickle cell trait during a medical exam. John Keilman,, "Mother of Great Lakes recruit who died during boot camp run seeks second autopsy, saying Navy has offered few answers on sickle cell-related death," 5 Nov. 2019 Yet sub-Saharan Africa is home to about two-thirds of the 20 million people with sickle cell disease and the 38 million living with HIV. Jon Cohen, Science | AAAS, "NIH and Gates Foundation lay out ambitious plan to bring gene-based treatments for HIV and sickle cell disease to Africa," 23 Oct. 2019 Given Vertex’s success in treating cystic fibrosis, the company has begun turning to other rare disorders that need effective medicines, from Duchenne muscular dystrophy to sickle cell diseases., "The FDA’s acting commissioner, Ned Sharpless, said the agency has been striving to speed the development of therapies for complex diseases.," 22 Oct. 2019 For some diseases, such as sickle cell, even 25 to 30 percent efficiency could alleviate some of the symptoms. Tanya Lewis, Scientific American, "New Gene Editing Tool Could Fix Genetic Defects, with Fewer Unwanted Effects," 21 Oct. 2019 New era for sickle cell disease Scientists have made progress toward developing a cure for the disabling blood disorder that causes intense pain and primarily affects black people. Jason W. Lloren,, "Bay Briefing: California’s power supply is getting greener," 23 Sep. 2019 However, since the genes for adult hemoglobin don’t produce healthy red blood cells in people with beta thalassemia and sickle cell disease, one treatment strategy is to introduce genetic changes that turn on fetal hemoglobin again. Time, "CRISPR Gene Editing Is Being Tested in Human Patients, and the Results Could Revolutionize Health Care," 6 Aug. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'sickle cell.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of sickle cell

circa 1923, in the meaning defined above

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Time Traveler for sickle cell

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The first known use of sickle cell was circa 1923

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Statistics for sickle cell

Last Updated

13 Dec 2019

Cite this Entry

“Sickle cell.” The Dictionary, Merriam-Webster Inc., Accessed 15 December 2019.

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More Definitions for sickle cell

sickle cell


Medical Definition of sickle cell

1 : an abnormal rigid, sticky red blood cell of crescent shape
2 : a condition characterized by sickle cells : sickle cell anemia, sickle-cell trait

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Rhyming Dictionary: Words that rhyme with sickle cell

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