se·​cre·​ta·​gogue si-ˈkrē-tə-ˌgäg How to pronounce secretagogue (audio)
: a substance stimulating secretion (as by the stomach or pancreas)

Examples of secretagogue in a Sentence

Recent Examples on the Web Others, known as secretagogues, stimulate the human pituitary gland to release excess growth hormone. Michael Powell, New York Times, 26 Mar. 2018 For those taking insulin and/or medications such as glipizide or glyburide (insulin secretagogues), exercise can cause low blood sugar if medication dose or carbohydrate intake is not adjusted appropriately. Trihealth,, 21 Aug. 2017

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'secretagogue.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


secretion + -agogue

First Known Use

1919, in the meaning defined above

Time Traveler
The first known use of secretagogue was in 1919

Dictionary Entries Near secretagogue

Cite this Entry

“Secretagogue.” Dictionary, Merriam-Webster, Accessed 21 May. 2024.

Medical Definition


variants also secretogogue
: a substance that stimulates secretion (as by the stomach or pancreas)
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