scleroderma

noun
sclero·​der·​ma | \ˌskler-ə-ˈdər-mə \

Definition of scleroderma 

: a usually slowly progressive disease marked by the deposition of fibrous connective tissue in the skin and often in internal organs and structures

Examples of scleroderma in a Sentence

Recent Examples on the Web

In a bid to lessen that risk, the family have considered moving to a colder climate but have ruled it out because Noelle has a condition called diffuse systemic scleroderma. Patricia Murphy, Fox News, "Boy who is allergic to sun can't go outside without thick plastic visor," 11 Apr. 2018 Lagares is pressing for that now, trying to gather more skin biopsies from scleroderma patients. Jennifer Couzin-frankel, Science | AAAS, "Pushing cells to self-destruct combats deadly fibrosis," 13 Dec. 2017 His daughter Suzanne Agee said the cause was respiratory failure as a complication of scleroderma, a degenerative disease in which the immune system harms healthy tissue. Steve Lohr, New York Times, "William Agee, ’70s C.E.O. Whose Star Was Dimmed, Dies at 79," 25 Dec. 2017 Agee, who spent his last months living in Seattle, died of scleroderma, a rare disease that causes hardening and tightening of the skin and connective tissues, his family said. John Sowell, idahostatesman, "William Agee, Boise native who headed Morrison-Knudsen, Bendix Corp., dies in Seattle," 20 Dec. 2017 Gene profiling of cells from scleroderma mouse models backed this up. Jennifer Couzin-frankel, Science | AAAS, "Pushing cells to self-destruct combats deadly fibrosis," 13 Dec. 2017 Both problems were triggered by a chronic autoimmune disease called scleroderma, a skin condition that can cause the skin to tighten or become thick and rigid, losing elasticity. Philly.com, "Medical mystery: Which risky problem gets treated first?," 30 July 2017 In 2015, a medical team at Oregon Health & Science University said there was no cure for her scleroderma. Janet Eastman, OregonLive.com, "Race car driver Ana Delfosse, who broke speed records and social barriers, remembered by Ashland friends (photos)," 4 June 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'scleroderma.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of scleroderma

circa 1860, in the meaning defined above

History and Etymology for scleroderma

New Latin

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The first known use of scleroderma was circa 1860

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More Definitions for scleroderma

scleroderma

noun
sclero·​der·​ma | \ˌskler-ə-ˈdər-mə \
plural sclerodermas also sclerodermata\ -​mət-​ə \

Medical Definition of scleroderma 

: a usually slowly progressive disease marked by the deposition of fibrous connective tissue in the skin and often in internal organs and structures, by hand and foot pain upon exposure to cold, and by tightening and thickening of the skin No treatment exists to reverse scleroderma, and when it moves to the digestive system, kidneys, heart, and lungs, it is often fatal.— J. Lee Nelson, Natural History, June 2001 When physicians suspect scleroderma, they may use several diagnostic tests to distinguish it from other connective tissue disorders.— Peta Gillyatt, Harvard Health Letter, May 1994

called also dermatosclerosis

More from Merriam-Webster on scleroderma

Britannica.com: Encyclopedia article about scleroderma

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