sclero·​der·​ma | \ ˌskler-ə-ˈdər-mə How to pronounce scleroderma (audio) \

Definition of scleroderma

: a usually slowly progressive disease marked by the deposition of fibrous connective tissue in the skin and often in internal organs and structures

Examples of scleroderma in a Sentence

Recent Examples on the Web Nurses who cared for Madison through the highs and lows of battling acute systemic scleroderma, a rare illness that affects the skin and other organs. Nikole Killion, CBS News, 16 May 2021 There is no cure for scleroderma, but immunosuppressants, along with an arsenal of steroids, anti-inflammatories and, weirdly, a common anti-malarial, can slow its progression. Aryn Baker, Time, 27 Mar. 2020 Despite the pain and debilitating nature of the scleroderma, Marcy remained a strong, loving, gracious, kind, and warm person who always put others first., 30 Oct. 2019 As the parent of a child with the chronic disease scleroderma, I’m not impacted by nor particularly interested in the glossy media coverage that Ms. Lukas says stigmatizes certain women. WSJ, 23 Dec. 2018 In a bid to lessen that risk, the family have considered moving to a colder climate but have ruled it out because Noelle has a condition called diffuse systemic scleroderma. Patricia Murphy, Fox News, 11 Apr. 2018 Lagares is pressing for that now, trying to gather more skin biopsies from scleroderma patients. Jennifer Couzin-frankel, Science | AAAS, 13 Dec. 2017 His daughter Suzanne Agee said the cause was respiratory failure as a complication of scleroderma, a degenerative disease in which the immune system harms healthy tissue. Steve Lohr, New York Times, 25 Dec. 2017 Agee, who spent his last months living in Seattle, died of scleroderma, a rare disease that causes hardening and tightening of the skin and connective tissues, his family said. John Sowell, idahostatesman, 20 Dec. 2017 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'scleroderma.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of scleroderma

circa 1860, in the meaning defined above

History and Etymology for scleroderma

New Latin

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The first known use of scleroderma was circa 1860

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Cite this Entry

“Scleroderma.” Dictionary, Merriam-Webster, Accessed 18 Aug. 2022.

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More Definitions for scleroderma


sclero·​der·​ma | \ ˌskler-ə-ˈdər-mə How to pronounce scleroderma (audio) \
plural sclerodermas also sclerodermata\ -​mət-​ə How to pronounce scleroderma (audio) \

Medical Definition of scleroderma

: a usually slowly progressive disease marked by the deposition of fibrous connective tissue in the skin and often in internal organs and structures, by hand and foot pain upon exposure to cold, and by tightening and thickening of the skin No treatment exists to reverse scleroderma, and when it moves to the digestive system, kidneys, heart, and lungs, it is often fatal.— J. Lee Nelson, Natural History When physicians suspect scleroderma, they may use several diagnostic tests to distinguish it from other connective tissue disorders.— Peta Gillyatt, Harvard Health Letter

called also dermatosclerosis

More from Merriam-Webster on scleroderma Encyclopedia article about scleroderma


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