round the twist
idiomatic phrase
        British,  informal      
      
                                
                                
              
          
                                                      : very angry, annoyed, or irritated                                      
              
                             
Her constant complaining is driving me round the twist.
                         
                
                                
            also                
          
                                                      : mentally unsound                                      
            
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  Merriam-Webster unabridged




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